Following viral transmission, fluid-filled vesicles and itchy lesions may appear at the end of an incubation period lasting 2 to 12 days. The spread and severity of these lesions can vary depending on the strength of the individual's immune system. However, more than half of individuals who come into contact with the virus may not show any symptoms. After entering the body, the virus settles in the nervous system and typically remains in an inactive (latent) state within the spinal nerve ganglia. Even in this state, carriers can transmit the virus to others through sexual contact. In situations where the immune system is weakened (e.g., due to stress, illness, or immunosuppression), the virus can reactivate, leading to the emergence of disease symptoms (outbreaks). Some carriers may never experience symptoms throughout their lives but continue to have the potential to transmit the virus. Others may experience four or more outbreaks per year.