The diagnosis of epididymitis is typically established through a physical examination. A digital rectal exam may be performed to assess for prostatic enlargement or tenderness. If urethral discharge is present, a sample may be collected for laboratory analysis to screen for sexually transmitted infections such as gonorrhea and chlamydia. Urine and blood samples are analyzed for any abnormalities. Color Doppler ultrasound can be utilized to evaluate blood flow to the testes, which helps in confirming the diagnosis of epididymitis by identifying any deviations from normal blood flow.