Anaphylaxis is a severe, life-threatening systemic allergic reaction that can develop due to various factors such as foods, chemicals, medications, and insect stings. This condition arises when the immune system overreacts to specific allergens. The primary causes of anaphylaxis-related deaths are typically delays in diagnosis and treatment, incorrect treatment applications, or an insufficient patient response to therapy.

During an anaphylactic reaction, the immune system releases potent chemicals that can cause shock. This release leads to a sudden drop in blood pressure and airway narrowing, causing breathing difficulties. Additionally, symptoms such as a rapid or weak pulse, skin rashes, nausea, and vomiting are frequently observed.

Anaphylaxis is an emergency and must be treated rapidly with an epinephrine injection. Any delay in treatment can lead to fatal outcomes.