The fundamental approach to treating fatty liver disease involves the patient making lifestyle modifications. Foremost among these changes are weight loss and the complete cessation of alcohol consumption. Research indicates that a 5% reduction in body weight initiates positive improvements in liver health, while a 10% weight loss leads to a significant regression of liver diseases.

Concurrently, effective management of diabetes and maintaining blood sugar levels within controlled limits through diet and medication is an important step in treating fatty liver disease. Similarly, high cholesterol and triglyceride levels should be reduced through an appropriate diet and suitable drug therapy. These lipid disorders are commonly observed in many fatty liver patients.

Studies have shown that cholesterol-lowering drugs can be beneficial for liver health in patients with elevated liver enzymes due to fatty liver and who also have high cholesterol/triglyceride levels. However, it is crucial to monitor liver function tests in every patient who starts cholesterol medication during the third or fourth month of treatment.

The most effective methods for weight loss are a balanced diet and regular exercise. The Mediterranean diet, in particular, is highly recommended as a very beneficial dietary model in this process. Regarding physical activity, the goal should be to engage in exercises such as walking, swimming, or gym activities three to four days a week. The resolute application of these steps can lead to a significant improvement in liver function.

If the disease progresses, a liver transplant may be considered as a last resort. However, patients with fatty liver disease, who are often overweight, constitute a special group in the transplant process, and the operation can be more challenging for them. Therefore, managing the disease through weight loss and exercise before it progresses should always be the priority.