Pilonidal sinus can largely be prevented by adhering to basic hygiene rules and making lifestyle changes. Regular and gentle skin care, including exfoliation to remove dead skin cells, is particularly important to prevent ingrown hairs in areas with dense hair follicles or where hair removal is performed. Key measures to prevent pilonidal sinus include: Pay attention to personal hygiene. Avoid tight underwear and clothing that may cause friction. Strive to maintain an upright posture when sitting for extended periods. To reduce the risk of obesity, eat healthily and adopt an active lifestyle.