The diagnosis of Sjögren's syndrome requires a comprehensive evaluation of various clinical findings and laboratory tests. The Schirmer test is used for the objective measurement of dry eyes. In blood tests, the presence of rheumatoid factor (RF) and specific autoantibodies such as anti-SSA/Ro and anti-SSB/La can aid in diagnosis. Additionally, findings such as anemia or leukopenia may be observed in some patients during a complete blood count. The definitive diagnosis of the disease is generally made through histopathological examination of a minor salivary gland biopsy. The compatibility of the biopsy result with Sjögren's syndrome is a crucial part of the diagnostic process.