The potential risk factors associated with spina bifida are closely related to the type and severity of the condition. Key potential complications include:

1. Hydrocephalus: The development of hydrocephalus is a significant concern in infants with spina bifida.
2. Cerebellar Herniation (Chiari Malformation): Cerebellar herniation may occur as a complication of spina bifida.
3. Infection Risk: There is a risk of infection developing either before or after the surgical closure of the spinal opening. Such infections can significantly worsen the patient's overall condition.