When piriformis syndrome is diagnosed, various treatment options, tailored specifically to the individual's condition, may be considered. These approaches typically include:
* Short-term muscle rest
* Home exercise programs, including stretching and strengthening exercises targeting the piriformis muscle
* Non-steroidal anti-inflammatory drugs (NSAIDs)
* Manual therapy or massage targeting the piriformis muscle
* Muscle relaxants
* Professional physical therapy and rehabilitation
* Steroid injections
* Botulinum toxin injections