In such cases, a definitive decision should not be made based on a single analysis. A second analysis should definitely be performed after approximately 3 weeks to confirm the results. If the same or similar results are obtained, investigations should primarily be conducted using genetic and hormone tests or testicular ultrasonography to obtain the necessary information. Afterwards, if necessary, the patient should be consulted with an andrologist-urologist. If no sperm is found in the sample, it is possible to obtain sperm from the testicles using a surgical method called Micro-TESE. Preferably, the TESE procedure is planned when the female partner's eggs are ready; after sperm is retrieved, egg retrieval is performed, followed by in-vitro fertilization. However, sometimes the micro-TESE operation can be performed for diagnostic purposes before the female partner is prepared. If sperm is found, it can be frozen and stored, and the female partner can be prepared later.