The most prominent clinical sign of anisocoria is one pupil being significantly larger than the other. While this may be the sole finding in some cases, various additional symptoms may be observed depending on the nature of the underlying cause or the progression of the condition. Other symptoms that may be associated with anisocoria include:
* Eye pain
* Blurred vision
* Double vision (diplopia)
* Sensitivity to light (photophobia)
* Sudden vision loss
* Headache
* Fever
* Nausea or vomiting
* Neck pain or stiffness