Before the procedure, patients receive detailed verbal information and provide written consent. The biopsy area is evaluated using ultrasonography or computed tomography (CT). The procedure site is then disinfected with an antiseptic, and a sterile field is prepared. Local anesthesia is administered to numb the relevant area. Under real-time ultrasound or CT guidance, a core biopsy needle, typically 1 to 4 mm in diameter, is advanced into the target tissue. Once in position, the needle's firing mechanism is activated, and a small internal blade rapidly extends to excise a tissue sample. This tissue sample is then carefully placed into a container containing a special pathological fixative. This process is repeated multiple times from different parts of the lesion to ensure adequate sampling. The procedure is concluded after a pathologist, who is present in the room, confirms the adequacy of the collected samples. This is an outpatient procedure, and its duration typically ranges from 15 to 30 minutes.