Bone cancer treatment involves various methods such as surgical intervention, radiation therapy, chemotherapy, and targeted therapy. The treatment plan is determined considering the type, size, spread of the tumor, and the patient's general health status.
Generally, the primary method of choice is the surgical removal of the cancerous bone tissue. This intervention is often performed as limb-sparing surgery; after the tumorous bone segment is removed, it is replaced with a metal implant (prosthesis) or bone tissue taken from another part of the body (bone graft) to preserve function. If the cancer is near a joint, such as the knee, removing the joint and replacing it with an artificial one can also be considered part of limb-sparing surgery. These approaches aim to maintain functionality without requiring the complete removal of the limb.
Other treatment options include radiotherapy, which is high-dose radiation treatment, and cryotherapy, which aims to eliminate cancerous cells from the tumorous bone using liquid nitrogen at -190 degrees Celsius. Chemotherapy, administered with drugs to destroy cancer cells or halt their growth, is also a significant treatment method.
However, if it is not possible to save the limb containing the tumor despite all limb-sparing surgical efforts, or if the limb's functionality is severely impaired, amputation (removal of the limb) may become an option. The decision for amputation is typically made in situations where the tumor is very large, there is insufficient soft tissue to cover the defect after removal, repair is not possible even with vascularized flaps, or the arm or leg has irreversibly lost its function.