Transferrin saturation is an important laboratory value reflecting iron metabolism in the body. The mineral iron plays an active role in vital functions such as the production of blood cells and the transport of oxygen throughout the body. Therefore, maintaining iron levels within a specific range is critically important for health.

Transferrin is a glycoprotein responsible for transporting iron in the bloodstream. Transferrin saturation indicates the relationship between the body's iron level and its capacity to transport iron. Numerically, this value represents the ratio of the transferrin protein in the serum to its total iron-binding capacity (TIBC). These values, commonly known as '% saturation,' are evaluated according to reference ranges. High or low transferrin saturation can provide clinically significant insights into various health issues.