Rickets is a growth disorder in children resulting from prolonged and significant deficiency of vitamin D, calcium, or phosphate. This condition is characterized by the softening and weakening of bones, leading to skeletal deformities. In addition to deficiencies in calcium, phosphate, and vitamin D, genetic factors can also contribute to the development of rickets in children in rare cases.
Vitamin D is an essential vitamin that supports the body's absorption of calcium and phosphorus from food. Without sufficient vitamin D, adequate levels of calcium and phosphorus cannot be maintained in the bones; this leads to the weakening and fragility of bone structures.
Rickets differs from a similar condition in adults called osteomalacia, as it exclusively affects children. Treatment is usually possible with vitamin D and calcium supplements under medical supervision, but additional medical interventions may be necessary if an underlying cause is present.