Hormone therapy can lead to various side effects by affecting the body's natural hormone production or by interfering with how hormones function. The type and severity of these side effects vary depending on the specific treatment administered and individual bodily responses. Since each patient's response to treatment can differ, the observed side effects vary from person to person and may also show differences based on gender.

1. Common Side Effects in Men Receiving Hormone Therapy for Prostate Cancer:
* Hot flashes
* Loss of libido and sexual function
* Decreased bone density (bone weakening)
* Diarrhea
* Nausea
* Breast tenderness and enlargement (gynecomastia)
* Fatigue

2. Common Side Effects in Women Receiving Hormone Therapy for Breast Cancer:
* Hot flashes
* Vaginal dryness
* Menstrual cycle irregularities in premenopausal women
* Loss of libido
* Nausea
* Mood swings
* Fatigue

3. Common Side Effects in Women Receiving Hormone Therapy for Uterine Cancer:
* Fluid retention (edema)
* Weight gain due to fluid retention
* Breast discomfort or tenderness
* Fatigue
* General feeling of malaise (unwellness, lassitude)
* Decreased sexual desire