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Adult-Onset Still's Disease (AOSD) is a rare type of inflammatory arthritis characterized by symptoms such as high fever, rash, and joint pain. It is the adult form of systemic-onset juvenile idiopathic arthritis (SJIA) seen in childhood. It typically affects adults under the age of 35, and its incidence is equal in men and women.
The disease is named after Sir George Frederic Still, who in 1897 described 22 children with systemic juvenile idiopathic arthritis, leading to the recognition of this disease.
Typical clinical manifestations of AOSD include high fever, skin rash, joint pain, and sore throat. The severity and combination of these symptoms can vary from person to person.
AOSD can cause permanent damage to joints, particularly the wrists. Treatment involves nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen to alleviate symptoms and control the course of the disease. If NSAIDs are insufficient, corticosteroids like prednisone may be used.
What is Adult-Onset Still's Disease?
The disease is named after Sir George Frederic Still, who in 1897 described 22 children with systemic juvenile idiopathic arthritis, leading to the recognition of this disease.
Typical clinical manifestations of AOSD include high fever, skin rash, joint pain, and sore throat. The severity and combination of these symptoms can vary from person to person.
AOSD can cause permanent damage to joints, particularly the wrists. Treatment involves nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen to alleviate symptoms and control the course of the disease. If NSAIDs are insufficient, corticosteroids like prednisone may be used.