Hand-foot-and-mouth disease (HFMD) is a contagious infection primarily caused by various enteroviruses, including Coxsackievirus A16 and Enterovirus 71. These viruses typically spread through direct contact. For instance, it can be transmitted by touching surfaces or objects contaminated with droplets expelled when an infected person coughs or sneezes. Transmission is also possible through direct contact with an infected person's saliva, nasal discharge, stool, and blister fluid. Although most common in infants and young children, the disease can affect people of all ages.