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Patient selection is crucial in this treatment. Successful outcomes are achieved in suitable patients.
In patients with malignant bone tumors, chemotherapy and sometimes radiotherapy are initially used to kill tumor cells in both the existing tumor tissue and any potentially circulating tumor cells. Preoperative chemotherapy reduces tumor size and helps control the cancer.
Following chemotherapy, the malignant bone tumor tissue is surgically removed. The bone affected by cancer is removed to ensure control of the tumor site. The removed bone is completely cleaned of cancerous soft tissues. The excised tumor tissue is sent for pathology to determine the effectiveness of the preoperative chemotherapy.
The bone affected by the malignant tumor and removed during surgery is immersed in liquid nitrogen for approximately 20 minutes. This process completely kills the bone. It is then left in a dry environment for 20 minutes and in physiological saline for 30 minutes to allow the frozen, dead bone to thaw. The killing of the bone also means the destruction of cancer cells.
These surgeries require the presence of surgeons experienced in bone tumors, as well as highly experienced microsurgery specialists. To restore skeletal function, a suitable replacement bone, including its blood vessels, is harvested from a donor site within the patient's body and implanted into the devitalized bone. Microsurgical techniques are crucial in this procedure, requiring meticulous stitching of small vessels.
Post-surgery, the devitalized bone is revascularized by the implanted living bone, allowing it to regenerate.
How is Cryosurgery Performed in Malignant Bone Tumors?
In patients with malignant bone tumors, chemotherapy and sometimes radiotherapy are initially used to kill tumor cells in both the existing tumor tissue and any potentially circulating tumor cells. Preoperative chemotherapy reduces tumor size and helps control the cancer.
Following chemotherapy, the malignant bone tumor tissue is surgically removed. The bone affected by cancer is removed to ensure control of the tumor site. The removed bone is completely cleaned of cancerous soft tissues. The excised tumor tissue is sent for pathology to determine the effectiveness of the preoperative chemotherapy.
The bone affected by the malignant tumor and removed during surgery is immersed in liquid nitrogen for approximately 20 minutes. This process completely kills the bone. It is then left in a dry environment for 20 minutes and in physiological saline for 30 minutes to allow the frozen, dead bone to thaw. The killing of the bone also means the destruction of cancer cells.
These surgeries require the presence of surgeons experienced in bone tumors, as well as highly experienced microsurgery specialists. To restore skeletal function, a suitable replacement bone, including its blood vessels, is harvested from a donor site within the patient's body and implanted into the devitalized bone. Microsurgical techniques are crucial in this procedure, requiring meticulous stitching of small vessels.
Post-surgery, the devitalized bone is revascularized by the implanted living bone, allowing it to regenerate.