Accurately determining the true prevalence of Herpes Simplex infection in individuals is challenging. The primary reasons for this difficulty include the infection's ability to remain in the body for long periods without showing symptoms (asymptomatic carriage) and approximately 65% of infected individuals being unaware of their condition. Furthermore, some individuals, especially those with HSV-2 infection, may be reluctant to report their illness due to reasons such as social stigma and shame. These factors lead to reported case numbers being significantly lower than the actual number of individuals carrying the virus. The prevalence of Herpes Simplex Virus (HSV) infection varies significantly among different communities and geographical regions. For instance, this rate is approximately 20% in the USA, 35% in Sweden, and around 40% in Brazil. While there is no definitive scientifically-based statistic for Turkey, estimates suggest a prevalence of approximately 30%. Risk groups where the infection is more frequently observed include populations with lower sociocultural and socioeconomic levels.