Allergic reactions can affect various systems of the body. The most commonly affected areas and their symptoms include:

* Respiratory Tract (Nose, Eyes, Sinuses, and Throat): Inhaling allergens triggers the release of histamine, leading to increased mucus production, swelling, and inflammation in the nose. This manifests as severe sneezing, nasal itching, watery and red eyes, and a sore throat.
* Lungs (Asthma): Asthma is a chronic condition characterized by hypersensitivity of the airways to environmental factors. Swelling in the airways and the mucosal membrane can restrict airflow, causing breathing difficulties. While asthma is not always allergic in origin, allergies frequently play a significant triggering role.
* Digestive System (Stomach and Intestines): Although most gastrointestinal discomfort stems from food intolerances, certain foods can cause allergic reactions. Key allergenic foods include peanuts, seafood, dairy products, and eggs. Cow's milk allergy in infants can lead to eczema, asthma, colic, and digestive problems. Conditions like lactose intolerance can cause stomach discomfort but operate through a different mechanism than allergies.
* Skin: Eczema and urticaria (hives) are common skin manifestations of allergies. Hives are characterized by itchy, raised lesions resembling insect bites. Food allergies may play a role in some cases of eczema.

Allergic conditions are observed to be more prevalent in developed countries. Factors such as stress, demanding work environments, increased air pollution, and food additives are thought to contribute to the rising prevalence of allergies.