The recurrence of the herpes virus can be triggered by various factors that weaken the immune system or cause local irritation. These factors include inadequate nutrition, excessive alcohol consumption, periods of intense stress, illnesses that exhaust the immune system such as influenza, menstrual periods, and local irritation.
Symptoms are generally most severe during the initial infection, but they can also be severe during subsequent recurrences due to the immune system's critical role in managing the virus. Disease symptoms can last up to 20 days. In women, cervical lesions may occur during an outbreak, leading to discharge and painful intercourse.
Herpes management during pregnancy requires special attention. While there are claims that a primary infection acquired in the first trimester of pregnancy can lead to severe fetal damage, there is insufficient scientific data on this matter, and potential damage may not be detectable by ultrasound. Therefore, it is recommended that all pregnant women be screened for a history of herpes infection early in pregnancy. In cases of a newly acquired active primary infection during pregnancy, particularly in the early stages, termination of pregnancy may be considered. For individuals who have previously had a herpes infection and are immune, there is generally no significant risk to the fetus. If a recurrence occurs in these pregnant individuals during pregnancy, supportive approaches are generally adopted instead of specific antiviral treatment. However, if active genital lesions are present near or during delivery, a Cesarean section is strongly recommended to prevent vertical transmission of the virus to the baby. Furthermore, great care must be taken in the postpartum period to minimize the baby's contact with the virus.