The treatment for Lupus (Systemic Lupus Erythematosus) is determined by a personalized approach based on the patient's specific symptoms and affected organ systems. Since each patient's condition and the course of the disease can vary, it is crucial to provide detailed, individualized information regarding treatment options and potential risks. Generally, antimalarial drugs and corticosteroids are commonly used in lupus treatment. Additionally, for some patients, non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants that regulate the immune system, or targeted biological agents may be preferred. These drug therapies are adjusted according to the severity of the disease, active symptoms, and overall course. It is critically important for patients to protect themselves from sunlight and to attend regular doctor appointments without interruption. Lifestyle modifications are also an integral part of the treatment; regular exercise, avoiding smoking, and a balanced diet are recommended. Furthermore, in patients with diagnosed Vitamin D and calcium deficiencies, appropriate supplementary treatments should be initiated.