Peroral Endoscopic Myotomy (POEM) is an advanced endoscopic procedure used in the treatment of achalasia and certain other esophageal (food pipe) disorders. This minimally invasive method involves endoscopically accessing the affected muscle fibers in the esophagus through the mouth and cutting them. This procedure aims to alleviate swallowing difficulties, especially those caused by achalasia, enabling patients to eat comfortably again. POEM is a specialized and advanced treatment offered only at select expert centers worldwide.