Symptoms of bone marrow cancers can vary significantly depending on factors such as the type, subtype, site of origin, and aggressiveness of the disease.

Common symptoms for Multiple Myeloma may include:
* Bone pain or fractures
* Persistent fatigue
* Frequent infections
* Changes in urinary frequency
* Cognitive changes (e.g., confusion)
* Increased thirst
* Nausea or vomiting
* Unexplained weight loss

Symptoms of Leukemia typically manifest as:
* Weakness and fatigue
* Shortness of breath
* Fever
* Bone pain
* Unexplained weight loss
* Night sweats
* Enlarged lymph nodes and spleen
* Frequent infections
* Pale skin
* Easy bruising
* Prolonged bleeding from minor wounds
* Generalized body aches (especially in bones)