For patients who do not benefit from first-line approaches in heel spur treatment, injection methods are introduced as a second-line treatment. These injections are generally administered with cortisone or, less commonly, Platelet-Rich Plasma (PRP) content. In patients whose pain complaints persist after the initial application, a second injection may be considered after an interval of 10-15 days. However, due to potential side effects and cortisone's ability to increase the risk of tears, especially in the plantar fascia, it is recommended to limit the total number of injections to two or at most three. For patients who do not observe the expected benefit from cortisone injections, PRP injections can be considered as an alternative option. Injection treatment can significantly reduce patients' pain, thereby improving their quality of life, and in some cases, provide long-term or permanent relief.