Because agoraphobia often develops as a fearful response to experiencing panic attacks, prevention of agoraphobia usually focuses on developing ways to cope with anxiety related to the possibility of another panic attack outside the person's home. Previously described treatments for agoraphobia are also generally used to prevent its development.

Alternatively, agoraphobia can be managed with lifestyle changes such as:

* Avoiding alcohol, drugs, and caffeine
* Maintaining a healthy and balanced diet
* Regular exercise
* Practicing breathing exercises