In the treatment of cardiovascular plaques, cholesterol-lowering and blood-thinning medications are primarily used. Control of risk factors is crucial in treatment. Cholesterol medications have significant effects in plaque regression and control. Age, sex, and genetic predisposition are unmodifiable factors. Controlling modifiable factors such as hypertension (high blood pressure), diabetes, and smoking is important in treatment. Hypertension, weight, and diabetes need to be controlled, and smoking must be ceased. Individuals with hypertension and diabetes must use their medications regularly.