Weight gain after this procedure can distort the shape of the buttocks. Weight gain is always disadvantageous, especially in patients who have had fat removed. Fat may accumulate again in the same area, although not as before, or in other areas, disrupting symmetry. Weight gain is advised against for all patients who have undergone liposuction, regardless of whether it was on the buttocks or another area.

Patients who already have excess fat and want to lose weight often undergo buttock augmentation or liposuction. Therefore, this group of patients needs to be careful in their later life. After fat transfer, there may be growth if the transferred fat is retained. This means that weight gain can also lead to growth in an augmented buttock. Conversely, weight loss can lead to some volume loss and sagging, and a slight reduction in the amount of transferred fat.