While the exact cause of adenomyosis is not fully understood, some factors are believed to play a role in its development. Potential risk and triggering factors may include:
* Postpartum uterine inflammation
* Structural abnormalities in the uterine wall tissue or invasion of endometrial tissue into the myometrium
* The role of stem cells found in the uterine muscle
* Hormonal factors
* Genetic predisposition
* Age
* Previous uterine surgical interventions