Otitis media medications are used to relieve pain and clear the infection.

Over-the-counter medications containing acetaminophen or ibuprofen can be taken to relieve pain.

Anesthetic ear drops can be used to alleviate pain if there is no perforation or rupture of the eardrum due to otitis media.

Otitis media drops can be ready-made or compounded in pharmacies.

Antibiotics, administered orally or as ear drops, are among the medications used to treat otitis media.

The benefit of decongestants used for nasal congestion and antihistamines used for allergies in the treatment of otitis media is debatable.