Key factors contributing to the development of calcification (osteoarthritis) include:
1. Joint Trauma: Fractures affecting the joint surface or inadequately/late treated joint dislocations.
2. Inflammatory Joint Diseases: Infectious or rheumatic joint inflammations that destroy joint cartilage.
3. Rheumatic Diseases: Various rheumatic conditions that can disrupt cartilage structure.
4. Neurological Causes: The joint's inability to perform its normal function due to conditions such as paralysis.