Polyneuropathy is a common condition observed in cancer patients. In some instances, polyneuropathy may be diagnosed before cancer, with subsequent investigations revealing an underlying malignancy, a phenomenon known as 'paraneoplastic syndrome'. Furthermore, certain chemotherapy drugs used in cancer treatment can induce polyneuropathy. Consequently, medical oncologists closely monitor patients undergoing chemotherapy for symptoms such as burning, coldness, numbness in the hands and feet, or rapid muscle fatigue.