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In the treatment of osteosarcoma, factors such as the tumor's type and stage, potential side effects, the patient's general health, and personal preferences are fundamental. Generally, chemotherapy and surgery are prominent as the main treatment methods. Radiotherapy (radiation therapy) is not a standard treatment for osteosarcoma and is generally not recommended. However, for patients unsuitable for surgery or those who prefer not to undergo surgery, it can be considered as a treatment option.