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Hairy Cell Leukemia (HCL) is a rare, slow-progressing type of blood cancer characterized by the excessive production of abnormal white blood cells (lymphocytes) in the bone marrow. This condition often leads to anemia and an increased susceptibility to bleeding and infections. HCL accounts for approximately 2% of all leukemia cases. It is more prevalent in men than women and typically manifests in middle-aged and older adults. While about 1,000 new cases are reported annually in the United States, specific regional incidence data may be limited. The name "hairy" refers to the distinctive, hair-like projections visible on the surface of these leukemic cells when examined under a microscope.