Liver transplantation is a surgical procedure in which a patient's diseased liver is replaced with all or part of a healthy liver from a donor. It is the definitive and often the only treatment option for chronic liver failure. Globally, cirrhosis is the most common reason for liver transplantation, followed by certain congenital diseases and some liver tumors. This highly complex procedure must be performed by an experienced and specialized team in a fully equipped medical center. Liver transplantation goes beyond being merely a surgical intervention. For a successful preparation, transplant, and post-transplant follow-up process, it is crucial that all units of the center, from operating rooms to laboratories, imaging units to intensive care, inpatient wards to other specialized departments, are of high quality and collaborate effectively.