Among the risk factors for liver cancer, chronic hepatitis infections, especially Hepatitis B and C, are paramount. Individuals with Hepatitis B and C have a 200 times higher risk of developing liver cancer compared to the general population. Approximately 80% of these cancer cases develop on the basis of cirrhosis.

Cirrhosis is a severe condition resulting from permanent damage to liver cells due to various causes such as alcohol, chronic hepatitis, or autoimmune diseases. Approximately 5% of patients with cirrhosis are at risk of developing liver cancer. While Hepatitis B can be effectively prevented through vaccination, treatments developed for Hepatitis C yield successful results.

Obesity is also a significant risk factor for liver cancer as it can lead to fatty liver and consequently cirrhosis. Regular medical follow-up for individuals at high risk is of great importance for early diagnosis and management.