Outbreaks of cholera are more common in warmer climates. Outbreaks sometimes occur after natural disasters such as earthquakes and hurricanes. These disasters can damage sanitation systems. Damage to sanitation systems leads to impaired water quality. Cholera outbreaks can also occur in areas lacking access to clean water sources.

However, cholera is also prevalent in areas experiencing overcrowding, war, and famine. Examples of such regions include parts of Africa, South Asia, and Latin America.