In cases of cryptogenic stroke, treatment is first planned to address the underlying cause based on the examination and test results. Investigations are carried out to determine if there is a tumor, cyst, vascular occlusion, or hemorrhage in the brain. If no clear cause is found, treatment with medication used in epilepsy is initiated; the type of seizure and EEG findings are evaluated, and medication is selected based on the physician's experience. Medications used in epilepsy treatment are started at a low dose to monitor for side effects, gradually increased, and adjusted to the appropriate dose. The patient is then monitored with regular check-ups and blood tests at intervals, depending on the medication's side effects.

Medication treatment should continue for at least two years provided there are no seizures. Then, medication tapering is planned gradually, based on the physician's recommendations and follow-up tests.