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Aspartate Aminotransferase (AST) is an enzyme found in tissues such as the liver, heart, and muscles. It is released into the bloodstream when any of these tissues are damaged. The AST test is an important marker used to detect liver damage and diagnose various liver diseases. It is also commonly known as SGOT (serum glutamic-oxaloacetic transaminase). In cases of liver damage, increased AST is released into the blood, leading to elevated AST levels.
An AST elevation is defined as exceeding the blood AST reference range (generally 8 to 33 U/L) and indicates a potential liver disease. Major conditions leading to AST elevation include liver cancer, chronic hepatitis, cirrhosis, and bile duct obstructions. High AST levels can manifest with symptoms such as nausea-vomiting, abdominal pain, jaundice, loss of appetite, and fatigue.
In healthy individuals, AST values generally remain within normal limits. While AST deficiency is usually not considered a cause for concern, in some cases it may indicate underlying health issues such as kidney diseases, diabetes, nutritional deficiencies, or vitamin B6 deficiency. As long as it is kept under control, AST deficiency typically does not present a dangerous situation.
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An AST elevation is defined as exceeding the blood AST reference range (generally 8 to 33 U/L) and indicates a potential liver disease. Major conditions leading to AST elevation include liver cancer, chronic hepatitis, cirrhosis, and bile duct obstructions. High AST levels can manifest with symptoms such as nausea-vomiting, abdominal pain, jaundice, loss of appetite, and fatigue.
In healthy individuals, AST values generally remain within normal limits. While AST deficiency is usually not considered a cause for concern, in some cases it may indicate underlying health issues such as kidney diseases, diabetes, nutritional deficiencies, or vitamin B6 deficiency. As long as it is kept under control, AST deficiency typically does not present a dangerous situation.