Fusion prostate biopsy offers significant advantages compared to conventional prostate biopsy. Prior to a fusion biopsy, a multiparametric prostate MRI is performed, allowing for precise targeting of suspicious lesions. As this method is typically performed under general anesthesia, patient comfort is maximized, and no pain is felt during the procedure. The most critical difference is that fusion biopsy detects aggressive prostate cancers, which have a high risk of being missed by conventional methods, with greater accuracy. This advanced diagnostic capability enables more precise treatment planning for patients, significantly reducing the risk of potential misdiagnosis and inappropriate treatment.