Agoraphobia typically develops as a reaction to the fear of experiencing panic attacks. Therefore, preventing agoraphobia generally focuses on developing ways to cope with the anxiety related to the possibility of another panic attack before leaving home. Treatments applied for agoraphobia are often also effective in preventing its development.

Additionally, agoraphobia can be managed through certain lifestyle changes, such as:
* Avoiding alcohol, drugs, and caffeine
* Adopting a healthy and balanced diet
* Engaging in regular exercise
* Practicing breathing exercises