Peritoneal cancer often presents asymptomatically in its early stages. Diagnosis is frequently made incidentally when peritoneal involvement is detected during imaging studies such as CT or PET scans performed for other reasons. During surgical exploration, patch-like tumor deposits may be observed on the peritoneum. As the disease progresses, the following symptoms may emerge:
* Accumulation of peritoneal fluid (ascites) in the abdomen, potentially leading to complaints such as umbilical hernia and shortness of breath.
* Abdominal pain and a sensation of bloating.
* Loss of appetite or reluctance to eat.
* Changes in urinary and bowel habits.
* Muscle wasting (atrophy).
* Nausea and constipation, sometimes alternating with diarrhea.
* Swelling, particularly in the ankles.
* Onset of respiratory difficulties.
* Unexplained weight gain or loss.
* Profound fatigue.
Furthermore, the growth of tumor cells can impair the functions of other intra-abdominal organs. For example, this may lead to intestinal obstructions due to narrowing of the bowel, or kidney failure resulting from obstructed urine flow.