To diagnose ALS, a detailed medical history of the patient is first evaluated, and a comprehensive physical and neurological examination is performed. Following these initial assessments, various laboratory and radiological tests are conducted to confirm the diagnosis or to rule out other conditions that may cause similar symptoms. These tests include: Electromyogram (EMG): A test that measures electrical activity in nerves and muscles. Blood tests. Cerebrospinal fluid test (Lumbar puncture). Magnetic Resonance Imaging (MRI): A test that produces detailed images of the body's internal structures without using X-rays.