Polycythemia treatment varies depending on the underlying cause. For instance, in cases of secondary polycythemia caused by obstructive sleep apnea, treating the primary cause helps to normalize and reduce the red blood cell count. However, there is no known cure for primary polycythemia, specifically Polycythemia Vera (PV). In such situations, treatment aims to effectively control the red blood cell count and minimize the risk of serious complications, such as blood clots.