Endoscopic Submucosal Dissection (ESD) is a procedure performed using endoscopes equipped with a high-resolution video camera and various specialized instruments. Patient preparation before the procedure varies depending on the area to be treated. For procedures in the large intestine, similar to colonoscopy preparation, bowel cleansing with medications recommended by the doctor is required. For procedures in the stomach, small intestine, or esophagus, at least 8 hours of fasting is sufficient. ESD is typically performed under anesthesia in an endoscopy unit. During the procedure, an endoscope, which has a high-resolution camera at its tip, is advanced to the target area. With the aid of specialized endoscopic cutting and bleeding control instruments passed through the working channel of the endoscope, the lesion is carefully removed in one piece from the surrounding healthy tissue.