Sjögren's syndrome is a chronic autoimmune disease that affects the body's moisture-producing glands, especially the salivary and tear glands. The most common symptoms arise from the dysfunction of these glands:

* Dry Mouth (Xerostomia): Occurs due to reduced saliva production. This can lead to difficulty swallowing and speaking, a burning sensation in the mouth, frequent dental caries, and mouth sores.
* Dry Eyes (Xerophthalmia): Results from insufficient tear production. Symptoms may include burning, stinging, itching, a gritty or foreign body sensation in the eyes, blurred vision, and light sensitivity.

Systemic symptoms can also occur when organs other than the moisture-producing glands are affected. These symptoms include:

* General Systemic Symptoms: Excessive fatigue, widespread muscle and joint pain, skin rashes, and dryness of the skin or vagina.
* Organ-Specific Symptoms: Symptoms related to the involvement of internal organs such as the lungs, kidneys, or liver; swelling behind the jaw and ears due to swollen salivary glands; and neurological findings like numbness in the arms and legs due to nerve involvement.

Sjögren's syndrome can occur on its own, but it is often seen in conjunction with other autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, primary biliary cholangitis, systemic sclerosis, polymyositis, Hashimoto's thyroiditis, and interstitial pulmonary fibrosis.