Various diseases are commonly observed in childhood, especially up to elementary school age. For instance, children can experience an average of 9 upper respiratory tract infections per year, and most of these are viral in origin. However, in children who frequently experience febrile illnesses, especially if the fever follows a cyclical pattern, periodic fever syndromes should be considered. Among these syndromes, one of the most common causes of true cyclical fever in children is PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis) syndrome.