The symptoms of amyloidosis can vary depending on the type of disease and the organs affected. However, generally observed symptoms of amyloidosis include:

* Severe fatigue and exhaustion
* Unexplained weight loss
* Joint pain and weakness
* Redness or bruising around the eyes
* Skin color changes or easy bruising
* Shortness of breath
* Numbness and tingling sensation in the legs
* Tongue swelling