No, gangrene starting in the legs with arterial problems ascends. However, varicose ulcers in varicose vein patients are not usually located at the tip of the toes, but around the ankle. This is the final stage of this skin disorder. It can take the form of ulcers ranging in size from hazelnut to apple-sized. However, if not treated well, it can lead to serious infections and problems. Therefore, treatment must be performed by a cardiovascular surgeon.